Drive Genomics Forward with DNBSEQ™ Technology

Complete Genomics developed its own patented DNA nanoball-based sequencing technology DNBSEQ™. Featuring DNBs (DNA NanoBalls) with high signal density on patterned nanoarray to greatly improve detection accuracy and efficiency, DNBSEQ boasts high performance in applications such as WGS (whole-genome sequencing)/WES (whole-exome sequencing) with low duplication rates and higher Indel accuracies. This innovative technology eliminates index hopping and clonal errors during the sequencing step of the workflow, facilitating greater accuracy and flexibility.

There is an increasing demand for whole genome sequencing (WGS), but cost is still a barrier for small-scale projects. To bring WGS to broader clinical use, efforts have been undertaken to further reduce cost and turnaround time while improving sequencing performance.

Rade’s talk will highlight how to accomplish completely PCR-free WGS – in which the whole process is not only PCR-free during library preparation, but also PCR-free during sequencing – via the DNBSEQ sequencing platforms.

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