DNBSEQ-G99

 DNBSEQ-G99 Enables Accurate MRD Detection With Invivoscribe Assays for Hematological Malignancies Please fill up the form to receive your download.

In this application note, we highlight the compatibility of Takara Bio’s SMART-Seq Human TCR (with UMIs) and the SMART-Seq Human BCR (with UMIs) with the DNBSEQ-G99 sequencing platform by Complete Genomics. Both kits adopt SMART technology and a 5’-RACE-based approach to capture full-length information from V(D)J variable regions of TCRs and BCRs, making them ideal tools for analyzing TCR and BCR repertoire diversity from bulk samples, including total RNA or purified cells. Unique molecular identifiers (UMIs) are incorporated to facilitate PCR error correction and clonotype quantification during data analysis.