1-9 of 21 results
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High-Resolution and Efficient Spatial Transcriptomics of the Rat Brain Using Stereo-seq, DNBSEQ, and SpatialX for Comprehensive Cell-Type Analysis
High-Resolution and Efficient Spatial Transcriptomics of the Rat Brain Using Stereo-seq, DNBSEQ, and SpatialX for Comprehensive Cell-Type Analysis Please fill up the form to receive your download. -
3-Dimensional Characterization of the Ovarian Tumor Immune Microenvironment Using Multi-Omic Analyses
This study demonstrates incorporation of multi-omics analyses with Stereo-Seq results to achieve unmatched characterization of the complex tumor immune microenvironment. Corroboration of spatial gene expression with previous findings, as well as strong similarity between sections within a sample demonstrate accuracy and precision of results. Novel marker genes within tumor subtypes may reveal new therapeutic targets. -
Performance and Compatibility Evaluation of Celemics NGS Panels with DNBSEQ-G400 Sequencing Platform
This study evaluates the performance of two Celemics library preparation kits and two target enrichment panels on the Complete Genomics DNBSEQ-G400 sequencing platform. Complete Genomics offers a full lineup of sequencers powered by its proprietary DNBSEQ™ technology. DNBSEQ utilizes Rolling Circle Replication (RCR) instead of traditional PCR amplification, resulting in highly accurate sequencing data with no clonal errors, index hopping, and low duplication rates. -
Performance and Compatibility Evaluation of Fluent Biosciences PIPseq and DNBSEQ-G400 Sequencing Platform
The DNBSEQ-G400 provides high sequencing quality (>93% Q30), is fully compatible with the PIPseeker analysis pipeline, and offers comparable or better sequencing results than the NextSeq 2000. Additionally, the generation of PIPseq sequencing data with the DNBSEQ-G400 system costs an estimated $0.11 per cell, making affordability an advantage of this scRNA-seq workflow. This work shows that coupling PIPseq and DNBSEQ technologies offers scientists an alternative scRNA-seq workflow that is both efficient and cost-effective for smaller validation studies or comprehensive, large-scale projects. -
Fast, High-Quality Immune Profile Sequencing with the Complete Genomics DNBSEQ-G99 Sequencer
In this application note, we highlight the compatibility of Takara Bio’s SMART-Seq Human TCR (with UMIs) and the SMART-Seq Human BCR (with UMIs) with the DNBSEQ-G99 sequencing platform by Complete Genomics. Both kits adopt SMART technology and a 5’-RACE-based approach to capture full-length information from V(D)J variable regions of TCRs and BCRs, making them ideal tools for analyzing TCR and BCR repertoire diversity from bulk samples, including total RNA or purified cells. Unique molecular identifiers (UMIs) are incorporated to facilitate PCR error correction and clonotype quantification during data analysis.