unleashing_the_power_of_dnbseq_stereo_seq_complete_genomics

In this interesting talk, Dr. Michael Snyder (Chair, Department of Genetics at Stanford University) showcases the powerful capabilities of sequencing technologies, highlighting Complete Genomics DNBSEQ and Stereo-seq technologies for high-throughput omics applications.

What you’ll learn:

  • Explore how a 1 cm² chip with 4.6B reads maps over 186,000 cells and profiles 56.6M transcripts across the human duodenum.
  • Stereo-seq revealed cellular niches at single-cell resolution, outperforming competing platforms in spatial precision.
  • How APP-CD74 interaction loss and mitochondrial gene proportions signal stressed neuronal regions in a spatially resolved manner.
  • Combining stLFR (Single Tube Long Fragment Reads) and PCR-free DNBSEQ short reads delivered comprehensive variant phasing and genome coverage for Dr. Snyder’s genome, achieving over 20M long fragments and 96.9% of genes in single contigs.
  • A seamless DNBSEQ workflow using Olink Explore HT library prep that processed 172 plasma samples measuring 5400+ proteins each, requiring 10B reads across 2 DNBSEQ-T7 flow cells, highlighting the high speed and massive scale.

Whether you’re decoding tissue heterogeneity, phasing long-range variants, or integrating multi-omics at scale, DNBSEQ and Stereo-seq technologies are redefining what’s possible in genomics.

Agenda:

mike-snyder-ashg-complete-genomics

Cutting Edge Omics Discovery by DNBSEQ Technology

Michael Snyder, Chair, Department of Genetics
Director, Center for Genomics and Personalized Medicine, Stanford University

Please fill out the form to access the on-demand webinar.