Media Coverage Archive
Northern California’s Top 5 Biotech Innovation News Stories
Xconomy | December 28, 2010 The year that was 2010 was another year on the rollercoaster. We had our ups and our downs. But throughout, we continued to be at the forefront of innovation. From mature companies to emerging technologies, 2010 was an exciting year.
>> read moreThe Genome: The Next 10 Years
PharmaVoice | December 31, 2010 In just one generation medicine will take a huge leap forward. That is, if researchers are right about how data from the human genome can be used to address disease.
>> read moreComplete Genomics Zeroes in on Tricks of Cancer Genome With Sequencing Service
Xconomy | December 9, 2010 Cancer cells pull many dirty tricks to resist therapy and stump researchers. One is a madcap reshuffling of the 3 billion letters of DNA that make up the genome found in healthy human cells. But now that genome sequencing has become so cheap and fast, Mountain View, CA-based Complete Genomics is trying to enter a new market that would have been impossibly expensive a couple years ago.
>> read moreThe mutation spectrum revealed by paired genome sequences from a lung cancer patient
Nature | May 27, 2010 Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small-cell lung carcinomas in smokers being the predominant form of the disease. Although previous studies have identified important common somatic mutations in lung cancers, they have primarily focused on a limited set of genes and have thus provided a constrained view of the mutational spectrum. Recent cancer sequencing efforts have used next-generation sequencing technologies to provide a genome-wide view of mutations in leukaemia, breast cancer and cancer cell lines.
>> read moreHuman Genome Sequencing on a Grand Scale
Drug Discovery & Development | September 15, 2010 Genetic variations—the way in which genes and proteins differ between individuals—can have important medical consequences. As a result, complete human genome sequencing has many potential drug discovery applications including an effective categorization of disease in molecular subtypes. Scientists can now sequence and compare a cancer patient’s tumor and normal genome to determine the genetic variations and pathway changes leading to the disease. This advance could lead to the discovery of new drug targets. Genome sequencing may also be used to streamline the clinical trial process by detecting in advance those subjects who are more likely not to respond to a drug or to experience side effects. It could also be used to rescue drugs that were not approved or removed from the market due to a rare but serious side effect by identifying the subset of patients who should not receive them.
>> read moreSomething New: An Interview with Radoje Drmanac
PLoS Genetics | August 19, 2010 Each year when I attend the American Society of Human Genetics meeting, I stroll up and down the vendor exhibits to see what's new, and, at the most recent meeting, I noticed one booth that stopped me in my tracks. The company was Complete Genomics, and I asked the rep about the cost of sequencing small stretches of the genome for a project in the lab. She told me they only do “complete” sequencing—full human genome sequencing. “That's why it's called ‘Complete’,” she added. OK, I get it—so how much does it cost? “$20,000 per sample if you order sequence for eight samples.”
>> read moreComplete Genomics Records $1.1M in Q2 Revenues, Discloses Some Equipment Providers
GenomeWeb | September 14, 2010 Complete Genomics posted approximately $1.1 million in revenues and a net loss of $12.6 million in the second quarter, according to documents filed last week with the US Securities and Exchange Commission. Thirteen customers accounted for the revenue the company recognized for the first six months of this year, the top customers being Pfizer, Sichuan University, and the International Mesothelioma Program at Brigham and Women’s Hospital. According to an amendment to its S-1 preliminary prospectus, which it initially filed in late July, research and development costs for the quarter increased to $4.9 million from $3.7 million during the year-ago quarter. General and administrative costs totaled $1.8 million, up from about $800,000 a year ago.
>> read moreComplete Genomics Posts Q2 Revenues of $1.1M
Genome Web | September 13, 2010 Complete Genomics posted revenues of $1.1 million for the second quarter, the firm disclosed Friday in an amended preliminary prospectus filed with the US Securities and Exchange Commission.
>> read moreComplete Genomics to Receive $1.1M for Sequencing 50 Tumor-Normal Pairs in NCI Pediatric Cancer Study
In Sequence | September 7, 2010 Complete Genomics said this week that it will be paid $1.1 million, or $11,000 per genome, to sequence and analyze 50 pediatric tumor-normal pairs for a National Cancer Institute-led study that is funded by the American Recovery and Reinvestment Act of 2009.
>> read moreWho has the lead in the $1K genome race?
Omics! Omics! | August 29, 2010 A former colleague and friend has asked over on a LinkedIn group for speculation on which sequencing platform will deliver a $1K 30X human genome (reagent cost only).
>> read moreComplete Genomics raises $39 million; faces Illumina lawsuit
Scrip | August 20, 2010 Complete Genomics, one of the companies chasing the holy grail of a whole human genome sequence at a cost of less than $1,000, has raised $39 million in a Series E funding round.
>> read moreIs the IPO Market Warming up to Genomics?
GenomeWeb | August 26, 2010 After years of being non-existent, recent activity suggests that the IPO market may be opening up to the sequencing space. But whether that will extend to the broader –omics market is debatable.
>> read moreComplete Genomics Files for IPO; Sequenced About 200 Human Genomes So Far this Year
GenomeWeb | August 3, 2010 Complete Genomics plans to raise up to $86.25 million in an initial public offering of its common stock, according to documents filed with the US Securities and Exchange Commission last week.
>> read moreAmazon’s Cloud Computing Service Sees Opportunity in Genomic Data Overload
Xconomy | July 6, 2010 The future of biology, if Amazon has its way, will be in the cloud. The Seattle-based online retailer (NASDAQ: AMZN) has generated buzz the past few years with its foray into cloud computing through Amazon Web Services.
>> read moreComplete Genomics emerges from stealth
Silicon Valley / San Jose Business Journal | October 6, 2008 Third-generation human genome sequencing company Complete Genomics Inc. announced its launch on Monday. The Mountain View-based company, which was established in March 2006, has been operating in stealth mode from a 32,000-square-foot facility. “For the past two and a half years, Complete Genomics has been reinventing the process of DNA sequencing based on pioneering technology invented by its founders and refined by a team of 100 employees with expertise in DNA engineering, molecular biology, instrumentation, semiconductors and high-performance computing,” the company said.
>> read moreCase Study: Complete Genomics--Fast, Cheap Sequencing Service
Technology Review | March/April 2010 Companies are struggling to make it fast, affordable, and profitable to sequence individuals' genomes--a tall order considering that until late 2008, fewer than 10 human genomes had been sequenced, and those at considerable expense. Four-year-old startup Complete Genomics, based in Mountain View, CA, thinks it has cracked the problem.
>> read moreSequencing's new race: Q&A with Clifford Reid, CEO of Complete Genomics
BioTechniques | February 24, 2010 In 2006, Clifford Reid, Radoje Drmanac, and John Curson came together to create Complete Genomics. The company was founded based on the shared idea that the most successful next-generation sequencing company would not only develop a next-generation sequencing platform, but establish a sequencing service. Since 2006, Complete Genomics has been in the development stages of their proprietary technology, and in February 2009, the company released their first complete human genome sequence.
>> read moreA Gene Factory Revs Up
Forbes Blog | February 22, 2010 A year ago, only a handful of people had ever had all their DNA sequenced. Now, a single company says it has already sequenced 50 human genomes, and plans to complete 500 more for paying customers.
>> read moreStep Right Up and Get Your Genome Here
NPR Health Blog | November 6, 2009 Though we're not convinced cataloging the contents of our genes is the greatest way to spend our money, it's sort of nice to know the price is dropping for a complete genome sequence.
>> read moreComplete Genomics Gets Gene Sequencing Under $5,000
Bloomberg | November 5, 2009 Complete Genomics, a Silicon Valley company backed by venture capitalists, produced complete sequences of three people’s DNA at an average cost of $4,500, accelerating the race to develop faster, cheaper gene-mapping systems.
>> read moreCompany Sequences Whole Human Genome for $ 1,700
Reuters | November 5, 2009 Want to know your entire DNA sequence? A California company has done it for as little as $1,700. Privately held Complete Genomics says it can do a better quality, usable genome map for about $4,400 -- compared with the $100 million the Human Genome Project spent to complete the first sequencing of the human genome in 2000. "Whole-genome sequencing costs have dropped from the more than $100 million cost of the first human genomes to the point where individual labs have generated genome sequences in a matter of months for material costs of as low as $48,000," the company's Radoje Drmanac and colleagues reported in the journal Science.
>> read moreFirm Says Low-Cost Genome Sequencing is Possible
HealthDay on US News & World Report | November 5, 2010 A genome sequencing company says it has developed a lower-cost DNA platforming sequence. Its report, including an analysis of data from three full human genomes, was published Nov. 5 in Science. The company, Complete Genomics, said the consumables cost for three genomic DNA nanoarrays ranged from $1,726 to just over $8,000.
>> read moreFirst-ever Association Study Using Whole Genome Sequences
Genetic Future Blog | November 3, 2009 New-technology DNA sequencing provider Complete Genomics will provide near-complete genome sequences of 100 individuals to the Institute for Systems Biology, driving the first ever association study for a complex trait using whole-genome sequencing. Here's the press release, and GenomeWeb has some additional information.
>> read moreComplete Genomics Details Low-Cost Sequencing Tech in Paper; Collaborators Encouraged by Results
In Sequence | November 10, 2009 "What's impressive is that they really have quite good coverage for outstanding quality, and that is what will allow this technology to catch people's attention," according to Pfizer's David Cox, one of the company's early-access customers.
>> read moreEmpresa le genoma completo por US$ 4.400
Folha de Sao Paolo (Brazil) | November 6, 2009 É de bater qualquer preço: cientistas conseguiram analisar o genoma inteiro de um ser humano por um preço médio de US$ 4.400 (R$ 7.500). Para comparar, quando se fez isso pela primeira vez, entre 1990 e 2003, custou US$ 3 bilhões. Ultimamente, o preço era de cerca de US$ 100 mil.
>> read moreErst 3 Genome fur je 3000 Euro, jetzt 100 Genome in 6 Monaten - Ist der nachste X-Prize bald fallig?
Deutsche Presse-Agentur (Germany) | November 6, 2009 Noch vor kurzer Zeit hätte diese Ankündigung eine Science- Fiction-Geschichte erwarten lassen: Ein US-Unternehmen will binnen 6 Monaten 100 menschliche Genome sequenzieren. Untersucht wird die DNA von Patienten mit Chorea Huntington, einer unheilbaren Krankheit des Nervensystems. Die US-Genetiker haben die Sequenzierung weit über die bisher möglichen Grenzen hinaus beschleunigt. Das persönliche Genom ist damit keine Frage mehr des Ob, sondern nur noch des Wann. Womöglich erhält das Unternehmen auch den „Archon Genomics X-Prize“ – er wird jenem zugesprochen, der 100 menschliche Genome in zehn Tagen für jeweils weniger als 10 000 Dollar sequenziert.
>> read moreBroad Institute to Pilot Complete Genomics' Sequencing Service
Genome Web | February 6, 2009 At the Advances in Genome Biology and Technology conference this week, the company also presented its first human genome sequencing data.
>> read moreSequencing Price Drops Even Lower
Technology Review | November 6, 2009 Complete Genomics, a start-up based in Mountain View, CA, has again lowered the stick in the financial limbo dance of human genome sequencing, announcing in the journal Science that it has sequenced three human genomes for an average cost of $4,400. The most recently sequenced genome--which happens to be that of genomics pioneer George Church--cost just $1,500 in chemicals, the cheapest published yet. A cost of about $1,000 is considered to be the price point at which average Americans might invest in having their genomes sequenced. The hope is that by making the process more affordable, genome analysis could become a routine part of medical care.
>> read moreBiotech Pioneer Lee Hood: Whole Families Will Get Whole Genomes Sequenced
Xconomy | March 10, 2010 Doctors and researchers in the future won’t just want to look at your genome to see how to treat or prevent illness. Instead, they will look at how all of an individual’s DNA compares with the closest members of their family, according to biotech pioneer Leroy Hood.
>> read more"Personal" study shows gene maps can spot disease
Reuters | March 10, 2010 Two studies published on Wednesday show it is possible to sequence the entire gene maps of families with inherited diseases and pinpoint the offending bit of DNA. The studies, which would not have been possible a year or two ago, are the first real delivery of the promised transformation of medical science from the Human Genome Project's mapping of the human genetic code.
>> read moreDisease hunting with whole genome sequences: the good news, and the bad news -- March 10, 2010
ScienceBlogs | March 10, 2010 Two new papers out today - the first ever studies to employ whole-genome sequencing for disease gene discovery - neatly illustrate both the promise and the challenges lying ahead both for clinical and personal genomics.
>> read moreNext-Generation Genome Sequencing Identifies Disease Genes
Bio-IT World | March 10, 2010 Two studies published this week show convincingly that whole-genome sequencing of individual patients or affected families can reveal the one gene out of some 25,000 in the human genome bearing a deleterious mutation.
>> read moreA scientist tracks the genetic origins of his own disease
Times Online | March 10, 2010 A scientist tracks the genetic origins of his own disease. In the introduction to his excellent book The Language of Life, which is published in the UK today (March 11), the genomics pioneer Francis Collins describes the family medical history of a Dr Robert James. One of several relatives affected by genetic disease is his father-in-law Fred, who is found to have a condition called Charcot-Marie-Tooth (CMT) syndrome.
>> read moreFamily of Four Gets Their Genomes Sequenced
Ars Technica | March 2010 Late last year, we described a genome sequencing technique that brought the price of consumables down to under $5,000. That technique, offered by Complete Genomics, has now been put to use: all the genomes have been obtained from a family of four in which both children suffer from two genetic disorders. In addition to identifying likely causative mutations, the full family pedigree has produced new measures of human mutation and recombination.
>> read moreFamily Genome Sequence Shows Mutations Less Common, Study Says
BusinessWeek | March 10, 2010 The gene sets of a four-member family were analyzed in research that suggested parents pass fewer gene mutations than thought to their offspring. Scanning the genomes of the family enabled the research team to pinpoint the mutations that caused two rare diseases in their children, according to a study in the journal Science. By comparing the DNA sequences of all four family members, the authors found that each parent gave 30 mutations, for a total of 60, to their children, the researchers said in a statement.
>> read moreISB-Led Team Publishes Whole-Genome Sequencing Study Involving Family of Four
GenomeWeb | March 11, 2010 Using Complete Genomics' human genome sequencing service, an American research team has identified mutations behind two inherited conditions within one family.
>> read moreDecoded Genome Gives New Hope in Confronting Diseases
New York Times | March 10, 2010 Two research teams have independently decoded the entire genome of patients to find the exact genetic cause of their diseases. The approach may offer a new start in the so far disappointing effort to identify the genetic roots of major killers like heart disease, diabetes and Alzheimer’s.
>> read moreNatural Selection - Discount DNA
Portfolio.com | December 17, 2008 Complete Genomics says it can sequence a human genome for a fraction of the current cost; a savings that could make DNA scanning affordable to millions.
>> read moreCut-price Genome Readings Point to Tests for All
The Times | November 9, 2009 The cost of reading the human genome — the DNA sequence — has been more than halved by a new approach. Complete Genomics, a company in California, has “sequenced” three human genomes using chemicals that cost an average of $4,400 (£2,600) a time, offering a cheap and powerful service to scientists investigating the links between DNA and health. The company intends to offer a $5,000 service next year.
>> read moreThe Next Big Thing: The Top 50 Venture-Backed Companies
Wall Street Journal | March 9, 2010 #7 Complete Genomics, Inc.: Complete Genomics breaks away from competitors in the DNA sequencing market by promoting itself as a service provider, rather than instrument seller. "Customers have us do the difficult work, and then [we] simply send them the data needed to do their research," says Clifford Reid, co-founder of Complete Genomics,
>> read moreComplete Genomics Sequences 14 Genomes
Technology Review | November 6, 2009 Complete Genomics, a start-up based in Mountain View, CA, has again lowered the stick in the financial limbo dance of human genome sequencing, announcing in the journal Science that it has sequenced three human genomes for an average cost of $4,400. The most recently sequenced genome--which happens to be that of genomics pioneer George Church--cost just $1,500 in chemicals, the cheapest published yet. A cost of about $1,000 is considered to be the price point at which average Americans might invest in having their genomes sequenced. The hope is that by making the process more affordable, genome analysis could become a routine part of medical care.
>> read moreSome Complete Genomics Pilot Customers Consider Larger Projects While Others Wait for Data
In Sequence | September 15, 2009 Complete Genomics is in discussions with some of its pilot customers regarding large-scale projects on the order of hundreds of genomes, company officials said.
>> read moreThe Next Big Thing
Stanford Magazine | May/June 2009 Fewer than 10 complete human genomes have been sequenced, which means we’ve only begun to scratch the surface of how genes that vary from person to person may influence health and disease. But that’s about to change.
>> read moreComplete Compute: An interview with Bruce Martin
Bio-IT World | September 23, 2009 Software engineer Bruce Martin’s chief claim to fame came early in his career. Hired straight out of school in the late ‘80s, he was a member of James Gosling’s team at Sun that developed Java. He moved onto other things as Java scaled up—mobile and email communications, banking and compliance—but nothing remotely close to life sciences. Martin’s latest challenge—building the IT and informatics infrastructure at Complete Genomics
>> read moreComplete Genomics Names Pfizer and PGP as Early Clients
Bio-IT World | September 8, 2009 Complete Genomics has named Pfizer, Duke University, Brigham & Women’s Hospital, the Ontario Institute for Cancer Research and the Flanders Institute for Biotechnology (VIB) among its first dozen clients for its human genome sequencing service. The company has delivered 14 genomes since March, in projects ranging from cancer to HIV susceptibility to schizophrenia.
>> read moreGetting Personal: The Promise of Cheap Genome Sequencing
The Economist | April 16, 2009 “Twenty years ago doctors had tight control over all medical information. We want that power to shift to individuals,” says Anne Wojcicki, a co-founder of 23andMe, a Californian genomics firm that counts Google as one of its investors
>> read moreEra of Personalised Medicine Awaits
BBC News | April 8, 2009 A revolution in genome screening has been promised by a biotech company in the US. Complete Genomics, says it will sequence one thousand complete genomes between June 2009 and the end of the year and one million over five years.
>> read moreComplete Genomics Presents First Human Sequencing Data at AGBT; Plans to Sequence Five Genomes for Broad Institute
In Sequence | February 10, 2009 The service, which Complete Genomics plans to launch in June, will charge customers, including genome centers, research institutes, and direct-to-consumer companies, $5,000 to sequence a human genome.
>> read moreGenome Sequencing: The Third Generation
Nature | February 6, 2009 Genome researchers gathered in a Florida hotel on 5 February, hoping to see whether companies that build 'third-generation' sequencing technologies can deliver on stunning claims such as sequencing human genomes in three minutes or selling them for $5,000. Although scientists were cautiously optimistic about the data unveiled, they still have major questions about how well this next generation of machines will work.
>> read moreComplete Genomics, Broad Institute Forge Cancer Sequencing Collaboration
Bio-IT World | March 3, 2009 Complete Genomics (CGI) has formally announced a collaboration with the Broad Institute to conduct complete human genome sequencing pilot studies of two cancers — glioblastoma and melanoma. Company founder, chairman and CEO Clifford Reid first made mention of the pending partnership during a lecture last month at the Advances in Genome Biology and Technology conference in Florida.
>> read moreComplete Genomics Details Its First Human Genome Assembly
Bio-IT World | February 6, 2009 MARCO ISLAND, Florida – Four months after stunning the next-generation sequencing community with its ambitious plans to launch a cut-price genome sequencing service, Complete Genomics CEO Clifford Reid presented details of its first human genome assembly on Thursday evening at the Advances in Genome Biology and Technology conference.
>> read moreComplete Genomics Nets $45M in Financing
GenomeWeb Daily News | August 24, 2009 The Series D financing will go to scale up a genome sequencing center, which is slated for a January launch.
>> read more