Letting the Genome Out of the Bottle
Comments on DNA sequencing technology and the coming era of genomic medicine
Should a Rich Genome Variant File End the Storage of Raw Read Data?
Deep sequencing of a human genome produces large datasets sized in the hundreds of gigabytes, while the associated genome variant file measures about half a gigabyte. Now that we are sequencing thousands of human genomes has the time come to store and use only this variant file?
Complete Human Genome Sequencing — Where Is It Headed?
Flashback to 1989: Rade’s vision was to sequence a complete human genome on one array.Updated to clarify point pertaining to clopidogrel
As chief scientific officer at Complete Genomics, I spend the majority of my time advancing complete human genome sequencing technology and its applications. Genome sequencing has been a passion of mine for almost 25 years, ever since I used my first hybridization-based DNA sequencing assay back in Belgrade, Serbia, in 1987. Even then, I wanted to be able to sequence a complete human genome on a single DNA microarray using microbeads.
First Impressions From a Genome Sequencing Factory
Blue light helps to preserve the color images produced during the sequencing process.It’s always eye-opening to learn what other people think about the place you work. If your work space is meticulous, is that the sign of an organized mind or someone who doesn’t have enough work to do? Is a cluttered desk a sign of genius?
Letting the Genome Out of the Bottle
Welcome to our new Complete Genomics Corporate Blog. Our purpose with this blog is to share ideas and facilitate conversation amongst key thought leaders, our customers and partners. We hope to discuss how we might move the genomics industry forward to tackle a whole host of challenges that it’s facing.
About This Blog
Dr. Clifford Reid
Chairman, President and CEO
Dr. Reid is a successful, serial entrepreneur. He enjoys commercializing disruptive computing and life sciences technologies.
Dr. Rade Drmanac
Chief Scientific Officer
Dr. Drmanac is a genome sequencing pioneer; his inventions include massively parallel DNA sequencing by hybridization and combinatorial probe ligation. As a group leader at the Argonne National Labs, he was part of the Human Genome Project. In 1993, he cofounded Hyseq, one of the first genomic companies.